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Face & Eye Serum

Face & Eye Serum

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1fl oz | 30 ml

Klotho Skin Cellular Face Serum

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The Cellular Repair Face Serum helps addresses the multi-level effects of aging, including fine lines wrinkles, elasticity and texture.



0.5 fl oz | 15 ml

Klotho Skin Cellular Eye Serum

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A proprietary blend of Second Generation Growth Factors, biomimetic peptides and other symbiotic ingredients provides anti-aging protection and a renewed youthful radiance to the eye area.

Clean, Sustainable, Proven


Klotho Skin ingredients are clean, sustainably sourced, and proven effective. All ingredients in Klotho Skin products are sustainably sourced. Klotho Skin products are responsibly packaged, using minimal plastics. Klotho Skin products are cruelty free, with absolutely no animal testing practices.

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  • Daily use helps improve appearance
  • Increased collagen production, smoothing out fine lines
  • Decreased collagen breakdown, slowing the development of fine lines and wrinkles
  • Decreased TEWL (Transepidermal Water Loss), increasing skin elasticity
  • Increase oxidative stress protection, encouraging even tone and texture
  • Increased anti-inflammatory responses, promoting healthy tone and appearance

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After cleansing and drying face, twist the cap of bottle to dispense serum onto clean hands. Gently pat serum into the skin in a circular motion. Wait 5 minutes for serum to dry and absorb before applying any moisturizer or sunblock.

Best results are seen when applied morning and night. All skin care products should be used for 21 to 28 days prior to evaluation to ensure full cell cycle results.

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Klotho Skin 28-Day Before & After gallery for proven results.

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ONE-TIME purchase


Try Klotho Skin’s Cellular Repair Face Serum once. Once you love the results, have it delivered monthly to your door.


$225 EVERY 2 months

Enjoy 10% off your monthly subscription purchase to have Klotho Skin delivered to your door.

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+ What is the difference between serum and cream/moisturizer?

Serums are highly concentrated anti-aging ingredients. Unlike moisturizers, they do not contain occlusive, or airtight, ingredients such as petrolatum or mineral oil that create a barrier on your skin. Because serums do not contain filler ingredients, they penetrate the skin faster and more effectively, requiring minimal amounts of product per application.

Klotho Skin uses Klotho enhanced cells to produce special cell conditioned medium contrary to second generation growth factor and the Klotho protein. These factors are then isolated and harvested to set the framework for Klotho activation and its resultant benefits. Studies have shown that fibroblasts treated with Klotho Skin cosmeceuticals can actually start producing collagen like a younger fibroblast cell.

+ What causes fine lines and wrinkles?

Dependent upon your age and skin type, fine lines typically appear around the eyes as signs of dehydration. Over time, the lines become permanent as signs of habitual movements, and moisture and collagen loss through oxidative stress.

As Klotho Skin products promote the upregulation of the Klotho gene, which ultimately increases the body's natural sodium dioxide levels and results in cellular protection against oxidative stress.

+ What is TEWL (Transepidermal Water Loss)?

TEWL is the process in which water passes from the dermis (middle layer) to the epidermis (outer layer) and evaporates from the skin’s surface.

While TEWL is a process that your skin naturally regulates, certain circumstances such as injury, low-humidity weather conditions and topically applied products can damage the skin’s barrier function can dry out the skin and affect TEWL levels.

+ At what age should I begin applying facial serum?

Klotho Skin recommends starting a facial serum at age 20, to encourage hydration and diminish fine lines under the eyes.

+ Is it too late to use facial serum?

It is never too late to take care of your skin. The active ingredients in Klotho Skin products work on all skins, at all ages.

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+ What are Human Fibroblasts?

Fibroblasts are the main connective tissues found in the body. A fibroblast cell is responsible for building the extracellular matrix (a framework that supports additional structures) and collagen (the element that fills the framework). Together, the matrix and collagen form the structural framework of tissues and play an important role in tissue repair. As the fibroblast ages , collagen production drops almost in half.

Klotho Skin uses Klotho enhanced cells to produce special cell conditioned medium containing second generation growth factor and the Klotho protein. These factors are then isolated and harvested to set the framework for Klotho activation and its resultant benefits.

+ What are growth factors?

Growth factors are polypeptides or proteins that play a key role in the regulation of a number of physiological processes. Topical application of growth factors also reduces signs of photoaging, promotes fibroblast and keratinocyte proliferation, and induces extracellular matrix formation.

The types of cytokines and growth factors number in the thousands, each with its specific action. For skin renewal, these would include Epidermal Growth Factor (EGF), Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor (FGF) amongst others. There are over 100 growth factors in total

+ The Role of Growth Factors in Ageing

When we are young, we have a high ratio of robust stem cells in our bodies, and they secrete potent cytokines that allow rapid healing and renewal processes within our skin. As we age, our stem cell count and activity diminish. As a result, our skin cells receive less cytokine and growth factor input, gradually losing its ability to effectively renew and repair itself. Our skin’s reduced ability to heal—from wounds and also from environmental and sun damage — results in hyperpigmentation, wrinkles, sagging, and other signs of aging skin. Exogenous growth factors collected from cell conditioned medium from cells invitro can effectively aid in cell renewal in invivo model. Because growth factors are essentially a large protein molecule. They are effective only if they can pass through our epidermal surface.

Liposomal technology allows the growth factors and the Klotho protein found in Klotho Skin to penetrate to the deeper layers beneath the surface skin so they may reach their target areas and do their regenerative work. Once through the epidermal layer, growth factors stimulate biochemical pathways that promote skin tissue repair and regeneration, and they promote the formation of collagen and elastic fibers which give the skin its softness and suppleness. There is a Synergistic interaction which occurs of multiple growth factors with other proteins in epidermis and dermis results in skin repair and regeneration.

In Klotho Skin we use highly purified fat free sunflower phosphatidylcholine (PC) for the structure of the liposomes. We use a proprietary blend of advicell k, phosphatidylcholine (PC) and hyaluronic acid in the actual liposome which is created with a Ytron ZC Quado In-line Shear system


+ Are Klotho Skin products fragrance free?

Klotho Skin uses plant essential oils within its ingredient list. Hints of fruit oil extracts can be recognized.

+ Were animals tested in the making of this product?

No animals were used for testing in the making of Klotho Skin products.

+ Were animals tested in the making of this product?

No animals were used for testing in the making of Klotho Skin products.



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