Where Gene Science Meets Regenerative Skincare

We are a US-based biotech company with over 25 years of research into the Klotho gene, pioneering advanced genetic technologies to shape the future of regenerative medical aesthetics. Our vision is to transform skin rejuvenation through second-generation growth factors, while our mission is to revolutionize cosmetics with integrity, quality, and excellence.

The Klotho Gene Secret

The Klotho gene is the first documented aging suppressor gene in mammals that can delay aging when overexpressed and accelerate aging when disrupted.

The Klotho gene was originally identified as a gene mutated in a mouse strain that exhibits a syndrome resembling human aging, including a shortened lifespan, skin atrophy, muscle atrophy, neuronal degeneration, arteriosclerosis, osteoporosis, and pulmonary emphysema.

In contrast, overexpression of the Klotho gene extends the lifespan of the mouse, living 31% longer and remaining younger in all systems. FOXO1 is increased, resulting in a rise in superoxide dismutase, which serves to protect cells from oxidative stress.

Patented Groundbreaking Manufacturing

Patented Groundbreaking Manufacturing

Patented process utilizing advanced genetic engineering techniques to modify adult mesenchymal stem cells upregulating the Klotho gene, leading to the production of the Klotho protein and second-generation growth factors using clean and sustainably sourced ingredients.

Providers

Patients

Clinical Trials

Klotho Skin is the first skincare line designed to harness the power of the age-suppressing Klotho protein utilizing the cell-conditioned medium from genetically modified stem cells.

In vitro studies have shown 40% reduction in DNA damage after UVA radiation. Clinical trials showed:

50%

reduction in
Photodamage

42%

reduction in
Erythema

38%

reduction in
Dyschromia

32%

reduction in
Wrinkles

(Study period: 4 months, using Cellular Repair Face Serum, Cellular Repair Eye Serum, and Cellular Repair Night Creme)

Before & After

Before & After

KLOTHO SKIN users start seeing results as soon as 4 weeks with ongoing improvement through 12 weeks of consistent daily use.

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