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In 1997, scientists discovered a gene responsible for extending the lifespan of cells. Researchers have studied the Klotho gene and found its age-suppressing properties can be activated.

Our founder, a geneticist and medical doctor, has developed a patented process which works with this age-suppressing gene and stem cells to bring you second generation and the Klotho protein. After 20 years in the making, this formula has been designed to rejuvenate, restore and renew your skin for a more youthful appearance. This is the first skin care product to work on a Gentical modified stem cells.



Klotho Skin is the first to isolate human mesenchymal cells, which are genetically modified to upregulate the Klotho Gene and produce Klotho protein as well as second generation growth factors. Through meticulous assay tests and refinements, the team at Klotho Skin discovered the most optimal concentration levels of the Klotho protein and second generation growth factors and the Klotho protein to help elongate the life of our cells. Klotho Skin may be the first skincare line to be preventative, regenerative, and protective.



The Klotho Skin mission is to offer a new solution to ageing utilizing the Klotho protein and second generation growth factors, with a socially conscious mindset, donating a percentage of the profits to a worthwhile organization.

Klotho Skin ingredients are clean, sustainably sourced, and proven effective. Just as Klotho Skin is dedicated to elongating cellular life, the company is also determined to improve and give new life to the lives of women affected by war. A portion of proceeds from every sale is donated to Women for Women International, an organization that supports the most marginalized women in countries affected by conflict and war. The nonprofit’s programs teach and provide women the skills, knowledge, and resources necessary to create sustainable change for themselves, their family, and community.


Dr. Humble is a medical doctor specifically in aesthetic anti-ageing based in San Francisco and Los Angeles locations. Her undergraduate studies were in genetics and regenerative medicine has been her passion. She lectures nationally and internationally on anti-ageing and aesthetic medicine. She is a frequent lecturer at the World Congress of Anti-Ageing Medicine and is a published author of research-based, medical and non-medical articles. Her published medical research articles can be found within medical journals including Dermatologic Surgery and the Journal of Facial and Plastic Surgery.

With a core belief that our external beauty should reflect the beauty we feel inside, Dr. Humble founded Klotho Skin with the intention to achieve a truly effective method to maintain youthful skin.



Gail Humble M.D. founded Klotho Skin with the intention to achieve a truly effective method to maintain youthful skin. For over twenty years, Dr. Humble has dedicated her career to anti-ageing research through commitments and partnerships with:



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